Evaluation of Enzymatic Changes in Sublethal Cyanide Poisoning

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Journal of plant Biochemistry & Physiology  focused on articles related to Plant Biosystems, Plant Ecology, Plant production science, Plant signaling & behavior, virology, mycology, bacteriology,  nematology, plant neurobiology.

Cyanide is a noxious chemical well-known for its characteristics as suicidal, homicidal and chemical warfare agent. It is generated in ample quantities from metal plating and finishing, mining and extraction of metals such as gold and silver, production of synthetic fibers and the processing of coal. However, discharge of cyanide containing wastes into the environment has birth considerable interest. Cyanide is found to be highly poisonous to living organisms, primarily due to the formation of complexes with metal ions that are present as enzyme cofactors. The notable effect of cyanide occurs with Fe3+ ion in cytochrome, thereby obstructing cellular respiration and hence, oxidative phosphorylation.

Cyanide remediation potential of plants is due to their ability to synthesize cyanogenic glucosides. Naturally, cyanogenic plants not only synthesize organic cyanides but are also imbue with efficient degradation potentiality. Example of such plants is Chromolaena odorata which is widely known to be effectively used as a therapy against several ailments. Recently, the plant has been employed in the remediation of cyanide from contaminated sites. Cyanide intoxication mediate pathologic effects on different tissues that precede alterations in biochemical parameters.

The results of the study clearly shows disruption in enzymatic activities in rats exposed to potassium cyanide and this may lead to a severe energy crisis at the cellular level and altered the intermediary metabolism. Decreased enzymatic activities in various tissues under cyanide intoxication indicate the switch over of metabolic pathways towards compensatory mechanisms. Therefore, alterations in the intermediary metabolism reflects the differential effects of stress and can be considered as a diagnostic tool in the assessment of cyanide poisoning in living organisms. Enjoy reading this article on journal website.

Journal of Plant Biochemistry & Physiology is focusing on releasing articles volume:8, Issue:1. Manuscripts can be submitted through online link or editorial office plantbio@echemistry.org

Thanks & Regards
Joseph Marreddy
Journal of Plant Biochemistry and Physiology
WhatsApp: +3225889658
Email  Id : plantbio@chemjournals.org

Journal of plant Biochemistry & Physiology  focused on articles related to Plant Biosystems, Plant Ecology, Plant production science, Plant signaling & behavior, virology, mycology, bacteriology,  nematology, plant neurobiology.

Cyanide is a noxious chemical well-known for its characteristics as suicidal, homicidal and chemical warfare agent. It is generated in ample quantities from metal plating and finishing, mining and extraction of metals such as gold and silver, production of synthetic fibers and the processing of coal. However, discharge of cyanide containing wastes into the environment has birth considerable interest. Cyanide is found to be highly poisonous to living organisms, primarily due to the formation of complexes with metal ions that are present as enzyme cofactors. The notable effect of cyanide occurs with Fe3+ ion in cytochrome, thereby obstructing cellular respiration and hence, oxidative phosphorylation.

Cyanide remediation potential of plants is due to their ability to synthesize cyanogenic glucosides. Naturally, cyanogenic plants not only synthesize organic cyanides but are also imbue with efficient degradation potentiality. Example of such plants is Chromolaena odorata which is widely known to be effectively used as a therapy against several ailments. Recently, the plant has been employed in the remediation of cyanide from contaminated sites. Cyanide intoxication mediate pathologic effects on different tissues that precede alterations in biochemical parameters.

The results of the study clearly shows disruption in enzymatic activities in rats exposed to potassium cyanide and this may lead to a severe energy crisis at the cellular level and altered the intermediary metabolism. Decreased enzymatic activities in various tissues under cyanide intoxication indicate the switch over of metabolic pathways towards compensatory mechanisms. Therefore, alterations in the intermediary metabolism reflects the differential effects of stress and can be considered as a diagnostic tool in the assessment of cyanide poisoning in living organisms. Enjoy reading this article on journal website.

Journal of Plant Biochemistry & Physiology is focusing on releasing articles volume:8, Issue:1. Manuscripts can be submitted through online link or editorial office plantbio@echemistry.org

Thanks & Regards
Joseph Marreddy
Journal of Plant Biochemistry and Physiology
WhatsApp: +3225889658
Email  Id : plantbio@chemjournals.org